Does hexproof prevent you from targeting your own permanent with your own spells?

Hexproof means the permanent (or player) can't be the target of spells or abilities your opponents control — but the rules are clear that the controller of a hexproof permanent also cannot target it with their own spells or abilities. CR 702.11b states: 'Hexproof on a permanent means that permanent can't be the target of spells or abilities your opponents control.' Wait — that actually says opponents, meaning your own spells can target your own hexproof permanent.

To clarify: Hexproof only stops opponents from targeting that permanent. You, as the controller, are freely allowed to target your own hexproof permanents with your own spells and abilities. CR 702.11b is explicit that the restriction applies only to spells and abilities controlled by opponents.

This is an important distinction from Shroud (CR 702.18), which prevents any player — including the controller — from targeting the permanent. Hexproof was designed specifically to protect against opponents while leaving the controller free to interact with their own permanents.

Concrete example: You control a Gladecover Scout (a creature with hexproof). Your opponent cannot target it with Lightning Bolt, but you can freely target it with your own Giant Growth to give it +3/+3. Hexproof poses no obstacle to you targeting your own creature.

So the answer is No — hexproof does not prevent you from targeting your own permanent with your own spells or abilities. It only protects against your opponents' spells and abilities (CR 702.11b).