A player loses the game due to an empty library only when they are required to draw a card and cannot (CR 104.3c). The key word is required: if the draw is skipped entirely, there is no attempt to draw, and thus no failure to draw.
CR 117.4 clarifies that if an effect says you skip a step or phase, the events that would normally occur in that step simply do not happen. Skipping your draw step (e.g., due to the card Necropotence or One with Nothing effects) means the mandatory draw of CR 504.1 never triggers at all.
By contrast, if anything else during that turn requires you to draw a card — say, a spell or ability that says 'draw a card' — and your library is empty, you would lose at that point, because that draw is not skipped.
Concrete example: You control Necropotence, which makes you skip your draw step. You have zero cards in your library. Your draw step arrives, is skipped, nothing happens, and the game continues normally. You do not lose.
So the condition is simple: as long as the draw is genuinely skipped (not just replaced), no library-empty loss occurs from that skipped draw.
Unofficial fan resource — not affiliated with or endorsed by Wizards of the Coast. Answers are AI-generated estimates grounded in the Comprehensive Rules and are not a substitute for an official judge. Verify anything match-critical.